I HAVE MADE THIS WEBSITE TO ENRICH THE KNOWLEDGE OF STUDENTS IN INDIA AS WELL AS ABROAD TO UNDERSTAND THE BASICS OF BIOCHEMISTRY WITHOUT COMPROMISING ON MOLECULAR DETAILS. I SINCERELY DO HOPE THAT THE SITE WILL PROVIDE A FIRM BASIS OF BIOCHEMISTRY TO BOTH THE UNDERGRADUATE AND POST GRADUATE SRUDENTS IN INDIA.

Chapter 1:  LIPID STRUCTURE

1. Lipid Structure
2. Lipids in Water : Structure
3. Dynamics of Membrane Lipids
4. Review:  Thermodynamics
5. Lipids in Water: Thermodynamics
6. Why do Single Chain Amphiphiles form Micelles not Bilayers, and Double Chain Amphiphiles from Bilayers and not Micelles?
7. What's New in Lipid Biochemistry

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Chapter 2:  PROTEIN STRUCTURE

1. The Structure and Property of Amino Acids
2. Composition, Sequence and Conformational Analyis of Proteins;
3. Understanding Protein Conformation
4. Proteins Folding - In Vivo and In Vitro
5. Laboratory Determination of DG^o for Protein Folding/Unfolding
6. Thermodynamics and IMF's in Protein Stability
7. Prediction of Secondary and Tertiary Structure From the Primary Sequence
8. What's New in Protein Chemistry: Protein Aggregates - Not Just  Junk
9.  MOLECULAR MECHANICS AND DYNAMICS

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Chapter 3:  CARBOHYDRATES

1. Monosaccharides and Disssacharides
2. Complex Oligosaccharides
3. Glycoproteins:  Biosynthesis and Function

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Chapter 4:  DNA, GENOMICS, AND PROTEOMICS

1. The Structure of DNA
2. The Central Dogma of Biology
3. The Language of DNA
4. Proteomics

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Chapter 5:  BINDING

1. Reversible Binding I: Equations and Curves
2. Reversible Binding II: Experimental Binding Curves, Kd, and Error Analysis
3. A Model Binding System: Myoglobin. Hemoglobin, and Dioxygen
4. Binding and the Control of Gene Transcription 
5. New Methods in Drug Development

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Chapter 6:  TRANSPORT AND KINETICS

1. Passive and Facilitated Diffusion
2. Steady State and Rapid Equilbirum Kinetics
3. Models of Enzyme Inhibition
4. More Complicated Enzymes

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Chapter 7:  CATALYSIS

1. Methods of catalysis
2. Mechanisms of enzyme-catalyzed reactions
3. Cofactors and Electron Pushing: Sources and Sinks
4. Enzyme catalyzed reactions in organic solvents
5. Ribozymes

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Chapter 8:  OXIDATION/PHOSPHORYLATION

1. The Chemistry of Dioxygen
2. Biological Oxidation Reactions - Dehydrogenases, Mono and Dioxygenases, and Oxidases
3. ATP and Oxidative Phosphorylation Reactions
4. Photosynthesis: The Light Reaction

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Chapter 9:  SIGNAL TRANSDUCTION

1. Energy Transduction: Uses of ATP
2. Signal Transduction: Neurochemistry
3. Signal Transduction at Cell Membranes: Protein Kinases/Phosphatases
4. Apoptosis - Programmed Cell Death  and Signal Transduction

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 Chapter 10: METABOLIC PATHWAYS

• Carbohydrate Metabolism

  • Glycolysis
    • Glycolysis & Gluconeogenesis
  • Kreb's - TCA - Citric Acid Cycle 
  • Pentose Phosphate Pathway
  • Glycogen Biosynthesis & Galactose Pathway

   

  Lipid Metabolism

• Activation of Fatty Acids
• Beta-Oxidation of Fatty Acids -- even chain
• Beta-Oxidation of Fatty Acids -- odd chain
• Beta-Oxidation of Polyunsaturated Fatty Acid
• Cholesterol Biosynthesis
  

Amino Acid Metabolism

• Kreb-Henseleit Urea Cycle
• Shikimate Pathway
• Phenylalanine and Tyrosine Biosynthesis
• Tryptophan Biosynthesis

Energy Metabolism

• Oxidative Phosphorylation
  • Chemistry of ATP Synthesis
• Coenzymes