|
Overall Reaction for the Pathway |
|
Chorismate + L-Glutamine + 5-Phosphoribosylpyrophosphate (PRPP) + Serine |
---> |
L-Tryptophan + L-Glutamate + Pyruvate + PPi + 2 H2O
+ CO2 + D-Glyceraldehyde-3-Phosphate |
|
|
 |
|
 |
|
|
Chorismate |
| |
|
L-Gln
L-Glu, Pyruvate |
 |
Anthranilate synthase | |
|
|
 |
|
|
Anthranilate |
| |
|
5-P-Ribosyl-PP (PRPP)
PPi |
|
Anthranilate-phosphribosyl transferase | |
|
|
 |
|
|
N-(5'-Phosphoribosyl)-anthranilate |
| |
|
|
 |
Phosphribosyl-anthranilate isomerase | |
|
|
 |
|
|
1-(O-Carboxyphenylamino)-1'-deoxyribulose-5'-phosphate |
| |
|
CO2, H2O |
 |
Indole 3-glycerol phosphate synthase | |
|
|
 |
|
|
Indole-3-glycerol phosphate |
| |
|
Serine
G-3-P, H2O |
|
Tryptophan synthase | |
|
|
 |
|
|
L-Tryptophan | |
|
